Depression is a psychiatric disorder characterized by feelings of worthlessness, guilt, sadness, helplessness, and hopelessness. It is different then normal sadness or grief from the loss of a loved one because it is persistent and severe. Clinical depression has many related symptoms trouble sleeping, eating disorders, withdrawal and inactivity, self-punishment, and loss of pleasure. People that are depressed do not like to do things they may usually like to. About one if four Americans will suffer from a depression over the course of their l ....