Bipolar Disorder: Its Causes and Effects At least 2 million Americans suffer from bipolar disorder, more commonly known as manic-depression. This illness usually begins in adolescence or early adulthood and continues throughout life. Although it may come into affect at any time, most individuals with the disorder experience their first mood episode in their 20’s. However, manic-depression quite often strike teenagers and has been diagnosed in children under 12. The risk of suicide among persons afflicted with bipolar illness is unrealis ....