A Comparison of "Of Mice and Men" and "The Great Depression An Eyewitness The Great Depression is comparable to Lennie and George's life. I would like to give a comparison of George Milton and Lennie Small to the Great Depression. The time that this story took place was during the Great Depression. John Steinbeck captured the reality of this most difficult time. During the Great Depression people needed to travel together to share chores and duties to make a living until something better came along. That is the way George and Lennie travel ....